Cushing's disease results from excessive production of cortisol, a hormone normally produced by the adrenal glands. This excessive cortisol production can result from abnormalities in the pituitary gland that cause excessive hormone secretion by the adrenal glands, by tumors within the adrenal glands themselves, or by a combination of these factors.
American Staffordshire Terrier
Single to multiple raised, hairless, lobulated white to pale pink skin or sometimes pigmented skin masses which may ooze an oily white material. Masses range in size from ¼” – 1” in diameter.
Lesions occur most commonly on the trunk, the legs, the digits (toe), the scrotum, the lips, the anus, and the nose. The lesions are typically ulcerated or cauliflower-like in appearance, bleed easily and are typically solitary.