Acral Lick Granuloma


An acral lick granuloma is a lesion, usually located on the distal part of one of the limbs of dogs, which is caused or worsened by the animal's obsessive licking of it. Damaged cells are believed to release pain-relieving endorphins that addict the dog to the licking and mutilation of the lesion.

The possible causes of the itching and licking behavior include:

  • Boredom
  • Trauma
  • Arthritis
  • Other joint problems
  • Allergies
  • Skin infection

Often it is difficult to ascertain whether the cause of the lick granuloma is due to an underlying condition or the dog's obsessive licking or a combination of both.

Treatment is usually lengthy and often only minimally effective in chronic lesions. Early interventions have the best chance of success. Some animals will respond to medical therapy by maintaining a milder form of the lesion.

Signs & Symptoms

Lick granulomas are skin wounds typically located on the distal area of the front leg or hind leg of a dog. Some dogs may have more than one lick granuloma at a time. These lesions usually appear as firm, raised, hairless areas of skin that may be hyperpigmented, or darkened with pigment, due to the dog's chronic licking of the area. The center of the lesion is usually ulcerated, red, and moist, or may be covered by a scab.

Causes & Transmission

The causes of acral lick granulomas include infections caused by bacteria, fungi, or mites; allergies, cancer, joint disease, or previous trauma; and an obsessive-compulsive disorder caused in some dogs by boredom. Dogs are incited by their condition to lick an area until they cause hair loss and erosion of the superficial skin layers. The consequence is further itching, which in turn results in more licking. This itch-lick cycle is exacerbated by the fact that damaged cells release endorphins, or brain chemicals, that are powerful analgesics. The licking may with time cause secondary infections, thickening of the skin, and changes in pigmentation.

Affected Animals

Acral lick granuloma may affect dogs of both sexes and all breeds; however, males or dogs that are older than five years are more often affected. Breeds disposed to this condition include the Great Dane, Doberman pinscher, Labrador retriever, Golden Retriever, German Shepherd, and Irish Setter.

Complications & Prognosis

Because acral lick granuloma is difficult to cure, veterinarians usually give it a guarded prognosis. Dogs that receive early treatment have a better prospect of recovery than dogs with chronic conditions.


Treatment of acral lick granuloma requires addressing the suspected cause of the lesions. Bacterial infections, for example, are treated with antibiotics for weeks to months. Arthritis is treated with pain management and joint therapy. The obsessive-compulsive component of the disease is more difficult to treat.

The dog may be prevented from licking the area by using some type of mechanical blocking device such as a collar, muzzle, or bandage. Oral antidepressant medications may be helpful. A topical product may be used to decrease the itchiness of the area and aid in the healing process. Severe cases may call for the injection of a corticosteroid into the lesion. If the lesion is small, it may be surgically removed, but recurrences are frequent. Radiation therapy has been tried in some cases, but its rate of success is poor. Laser surgery may be helpful in selected cases.


There are few recommended measures for prevention. Dogs suffering from boredom or from the stress of being left alone for too long should be given a more stimulating and socially interactive environment.